Invitrogen™ GBP5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA583024

Product Code. 16339984

Description

Immunogen sequence: TDQALTETEK KKKEAQVKAE AEKAEAQRLA AIQRQNEQMM QERERLHQEQ VRQMEIAKQN WLAEQQKMQE QQMQEQAAQL STTFQAQNRS LLSELQHAQR TVNNDDPCVL L Highest antigen sequence indentity to the following orthologs: Mouse - 41%, Rat - 44%.

The guanylate-binding proteins (GBPs) are a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN). GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble but not crystalline inflammasome priming agents.

Specifications

• Antigen: GBP5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GBP5
• Gene Alias: 5330409J06Rik; GBP5; GBP-5; Gbp5a; GBP-TA antigen; GTP-binding protein 5; Guanine nucleotide-binding protein 5; guanylate binding protein 5; guanylate nucleotide binding protein 5; guanylate-binding protein 5; muGBP-5; UNQ2427/PRO4987
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 115362
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96PP8
• Gene Symbols: GBP5
• Immunogen: Recombinant protein corresponding to Human GBP5. Recombinant protein control fragment (Product #RP-94338).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG