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Description
Immunogen sequence: INQYSLTVGL DLGPHDTKSL LKCVESLSFI VRDAAHITPD NFELCVKTLR IFVEASLNGG CKSQEKRGKS HKYDSKGNRF K Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 98%.
This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene.
Specifications
Specifications
| Antigen | GBF1 |
| Applications | Immunohistochemistry (Paraffin), Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | GBF1 |
| Gene Accession No. | Q92538 |
| Gene Alias | 1700083E03Rik; AI035702; ARF1GEF; AW049900; BFA-resistant GEF 1; Gbf1; golgi brefeldin A resistant guanine nucleotide exchange factor 1; golgi-specific brefeldin A-resistance factor 1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1; KIAA0248; mKIAA0248 |
| Gene Symbols | GBF1 |
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