Invitrogen™ GBA3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA596825

Product Code. 16549661

Description

Immunogen sequence: MAFPAGFGWA AATAAYQVEG GWDADGKGPC VWDTFTHQGG ERVFKNQTGD VACGSYTLWE EDLKCIKQLG LTHYRFSLSW SRLLPDGTTG FINQKAIQLD KVNLQVYCAW SLLDNFEWNQ GYSSRFGLFH VDFEDPARPR VPYTSAKEYA KIIRNNGLEA HL; Positive Samples: Jurkat, HepG2, SW480, Raji, A-549, Mouse kidney; Cellular Location: Cytoplasm, cytosol.

GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides. GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism.

Specifications

• Antigen: GBA3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GBA3
• Gene Alias: CBG; CBGL1; Cytosolic beta-glucosidase; cytosolic beta-glucosidase-like protein 1; Cytosolic GCase; Cytosolic glycosylceramidase; Gba3; GLUC; Glucosidase beta acid 3; glucosidase, beta, acid 3; glucosidase, beta, acid 3 (cytosolic); Glucosylceramidase beta 3; glucosylceramidase beta 3 (gene/pseudogene); klotho-related protein; KLRP
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57733
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.41 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9H227
• Gene Symbols: GBA3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-162 of human GBA3 (NP_0011219041).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG