Invitrogen™ GBA Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5145479

Product Code. 17960263

Description

GBA encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: GBA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GBA
• Gene Alias: acid beta glucosidase; acid beta-glucosidase; Alglucerase; betaGC; beta-GC; Beta-glucocerebrosidase; Cholesterol glucosyltransferase; Cholesteryl-beta-glucosidase; D-glucosyl-N-acylsphingosine glucohydrolase; Gba; GBA1; GBAP; GBAP1; GC; GCase; GCB; GLUC; glucocerebrosidase; glucosidase, beta, acid; glucosylceramidase; glucosylceramidase beta; glucosylceramidase beta pseudogene 1; glucosylceramidase-like protein; imiglucerase; Lysosomal acid GCase; Lysosomal acid glucosylceramidase; lysosomal glucocerebrosidase; SGTase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2629
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene Accession No.: P04062
• Gene Symbols: GBA
• Immunogen: Recombinant Human GBA protein, Ala40-Gln536 (Accession #P04062).
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG