Invitrogen™ Ganglioside GM2 Chimeric Recombinant Rabbit Monoclonal Antibody (KM966)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA551582

Product Code. 30087802

Description

Specificity: This antibody recognizes and binds ganglioside GM2.

Ganglioside GM2 is a glycosphingolipid found in the plasma membrane of cells, particularly in the nervous system. It is composed of a ceramide lipid tail and a complex carbohydrate head group that contains sialic acid residues. The function of Ganglioside GM2 is not fully understood, but it is believed to play a role in cell signaling and communication, as well as in the formation and maintenance of the myelin sheath that surrounds nerve cells. Mutations in the genes responsible for the synthesis or degradation of Ganglioside GM2 can result in various neurological disorders, including Tay-Sachs disease and Sandhoff disease.

Specifications

• Antigen: Ganglioside GM2 Chimeric
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Immunogen: This chimeric antibody was generated by cloning the variable heavy and light chain sequences of murine parent antibody KM696 (IgM) and expressing it as a mouse/human IgG1. The parent antibody was raised against human GM2.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Functional Assay, Immunocytochemistry
• Clone: KM966
• Conjugate: Unconjugated
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG κ