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Invitrogen™ GALNT6 Polyclonal Antibody

Description
Recommended positive controls: 293T, A431, H1299, Molt-4, PC-12. Predicted reactivity: Mouse (92%), Rat (91%), Xenopus laevis (80%), Chicken (82%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin.
Specifications
Specifications
| Antigen | GALNT6 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.79 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 20% glycerol and 0.025% ProClin 300; pH 7 |
| Gene | GALNT6 |
| Gene Accession No. | Q8NCL4 |
| Gene Alias | 4632410F13; AW047994; fc23d02; fc56f12; GalNAc transferase 6; GalNAcT6; galNAc-T6; GALNT6; N-acetylgalactosaminyltransferase T-6; polypeptide GalNAc transferase 6; Polypeptide N-acetylgalactosaminyltransferase 6; pp-GaNTase; pp-GaNTase 6; protein-UDP acetylgalactosaminyltransferase 6; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6; UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 6; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6); wu:fc23d02; wu:fc56f12; zgc:77836 |
| Gene Symbols | GALNT6 |
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