Invitrogen™ GAK Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA599201

Product Code. 16613455

Description

Antibody detects endogenous levels of total GAK.

GAK serine/threonine kinase or Cyclin-G-associated kinase was originally identified as a protein that is associated with cyclin G. However, neither CDK5 nor GAK kinase activity is activated by cyclin G nor does GAK affect CDK5 kinase activity. GAK seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.

Specifications

• Antigen: GAK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GAK
• Gene Alias: auxilin-2; cyclin G associated kinase; cyclin G-associated kinase; cyclin-G-associated kinase; D130045N16Rik; DNAJ26; DNAJC26; GAK
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 231580, 2580
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O14976, Q99KY4
• Gene Symbols: GAK
• Immunogen: A synthesized peptide derived from human GAK(Accession O14976), corresponding to amino acid residues K109-V159.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG