Invitrogen™ GABRQ Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA589095

Product Code. 16537121

Description

Immunogen sequence: NYLFYSRGPR RQPRRHRRPR RVIARYRYQQ VVVGNVQDGL INVEDGVSSL PITPAQAPLA SPESLGSLTS TSEQAQLATS ESLSPLTSLS GQAPLATGES LSDLPSTSEQ ARHSYGVRFN GFQADDSIIP TEIRNRVEAH GHGVTHDHED SNESLSSDER HGHGPSGKPM LHHGEKGVQE AGWDLDDNND KSDCLAIKEQ FKCDTNSTWG LNDDELMAHG QEKDSSSESE DSCPPSPGCS FTEGFSFDLF N; Positive Samples: Jurkat; Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse.

The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, theta subunit. GABRQ gene is mapped to chromosome Xq28 in a cluster including the genes encoding the alpha 3 and epsilon subunits of the same receptor. This gene location is also the candidate region of 2 different neurologic diseases:early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3).The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, theta subunit. It is mapped to chromosome Xq28 in a cluster including the genes encoding the alpha 3 and epsilon subunits of the same receptor. This gene location is also the candidate region of 2 different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3).

Specifications

• Antigen: GABRQ
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GABRQ
• Gene Alias: GABA(A) receptor subunit theta; GABA(A) Theta; GABRQ; gamma-aminobutyric acid; gamma-aminobutyric acid A receptor, theta; gamma-aminobutyric acid (GABA) A receptor, subunit theta; gamma-aminobutyric acid (GABA) A receptor, theta; gamma-aminobutyric acid (GABA) receptor, theta; gamma-aminobutyric acid (GABA-A) receptor, subunit theta; gamma-aminobutyric acid A receptor, theta; gamma-aminobutyric acid receptor subunit theta; gamma-aminobutyric acid type A receptor subunit theta; gamma-aminobutyric acid type A receptor theta subunit; THETA
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55879
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.53 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q9UN88
• Gene Symbols: GABRQ
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 350-600 of human GABRQ (NP_0610283).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG