Invitrogen™ GABRA2 Monoclonal Antibody (N399/19)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA527702

Product Code. 16342214

Description

A 1:100 dilution of MA5-27702 was sufficient for detection of GABA-A R, Alpha2 in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 55kDa. Does not cross-react with GABA-A Receptor Alpha1. This antibody was formerly sold as clone S399-19.

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: GABRA2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.4
• Gene Accession No.: P23576, P26048, P47869
• Gene Symbols: GABRA2
• Immunogen: Fusion protein amino acids 350-385 (Cytoplasmic C-terminus) of rat GABA-A Receptor Alpha2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
• Clone: N399/19
• Conjugate: Unconjugated
• Gene: GABRA2
• Gene Alias: C630048P16Rik; FLJ97076; GABA(A) receptor; GABA(A) receptor subunit alpha-2; GABA(A) receptor, alpha 2; GABAARalpha2; Gabra2; Gabra-2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, alpha 2; gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 2; gamma-aminobutyric acid A receptor alpha 2; gamma-aminobutyric acid receptor A2 subunit; gamma-aminobutyric acid receptor subunit alpha-2; gamma-aminobutyric acid type A receptor alpha2 subunit
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 14395, 2555, 289606
• Content And Storage: -20°C
• Form: Liquid