Invitrogen™ GABARAP Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA534559

Product Code. 15365481

Description

A suggested positive control is K562 cell lysate. PA5-34559 can be used with blocking peptide PEP-1602.

Gamma-aminobutyric acid (GABA) is the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing in the central nervous system. It has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. GABARAP (GABAA receptor-associated protein) links GABAA receptors to the cytoskeleton and may play a role in intracellular transport of GABAA receptors and its interaction with the cytoskeleton. GABARAP belongs to the MAP1 or ATG8 like family and recent studies show that MAPK15/ERK8 is acting through interaction with ATG8 family proteins to regulate autophagy.

Specifications

• Antigen: GABARAP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GABARAP
• Gene Alias: ATG8A; FLC3B; FLJ25768; GABA type A receptor-associated protein; GABA(A) receptor-associated protein; GABA-A receptor-associated protein; Gabarap; GABARAP a; GABARAP-a; gamma-aminobutyric acid receptor associated protein; gamma-aminobutyric acid receptor-associated protein; gamma-aminobutyric acid reseptor associated protein; HT004; hypothetical protein; MGC120154; MGC120155; MM46
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11337, 56486, 58974
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: O95166, P60517, Q9DCD6
• Gene Symbols: GABARAP
• Immunogen: A 19 amino acid peptide near the amino terminus of human GABARAP.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG