GAB2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16831975	Proteintech 22549-1-AP-20UL	20 μL
16821975	Proteintech 22549-1-AP-150UL	150 μL

Description

This gene is a member of the GRB2-associated binding protein (GAB) gene family and is similar to the GAB1 gene. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

Specifications

• Antigen: GAB2
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Mouse, Human
• Gene Accession No.: Q9UQC2, Q9Z1S8
• Gene ID (Entrez): 14389, 9846
• Immunogen: GAB2 Fusion Protein Ag18192
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: GAB2

• Concentration: 0.17 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: GAB2, GRB2 associated binder 2, KIAA0571, pp100
• Gene Symbols: GAB2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody