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Invitrogen™ G6PD Recombinant Rabbit Monoclonal Antibody (K01_1R70)
Description
G6PD Recombinant Monoclonal Antibody for IHC (P), Western Blot
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
Specifications
Specifications
| Antigen | G6PD |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | K01_1R70 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 50mM tris glycine with 150mM NaCl, 40% glycerol, 0.05% BSA and 0.01% sodium azide; pH 7.4 |
| Gene | G6PD |
| Gene Accession No. | P05370, P11413 |
| Gene Alias | G28A; G6PD; G6PD1; G6pd-1; G6pdx; Glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate 1-dehydrogenase X; glucose-6-phosphate dehydrogenase; glucose-6-phosphate dehydrogenase X-linked; Gpdx |
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