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Invitrogen™ FZD7 Polyclonal Antibody
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Product Code. 17109563
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Quantity:
100 μL
Unit Size:
100µL
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17109563 100 μL 100µL
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Product Code. 17109563 Supplier Invitrogen™ Supplier No. PA5111642

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: CVGQNTSDGS GGPGGGPTAY PTAPYLPDLP FTAL Highest antigen sequence indentity to the following orthologs: Mouse - 88%, Rat - 88%.

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FZD7
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene FZD7
Gene Accession No. O75084
Gene Alias frizzled 7, seven transmembrane spanning receptor; frizzled class receptor 7; frizzled family receptor 7; frizzled homolog 7; frizzled homolog 7 (Drosophila); Frizzled, drosophila, homolog of, 7; frizzled-7; Fz7; Fz-7; FZD7; FzE3; hFz7; LOC100360552; mFz7; rCG22430-like; rizzled 7
Gene Symbols FZD7
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human FZD7. Recombinant protein control fragment (Product #RP-107678).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8324
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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