Invitrogen™ FUZ Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA531699

Product Code. 13446227

Description

Recommended positive controls: HCT116. Predicted reactivity: Mouse (88%), Bovine (87%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

FUZ is the human homolog of Drosophila fy protein and belongs to the fuzzy family. The fy gene of Drosophila encodes a novel four-pass transmembrane protein that plays two roles in the development of hairs on the Drosophila wing. The first is to specify the correct orientation of the hair by restricting its initiation to the distal vertex of the cell. The second role is to permit the development of just a single cell hair by maintaining the integrity of the F-actin and microtubule arrays that are required for hair development. In humans, the protein is involved in cytoskeleton function and cell polarity in epithelial cells. The human fuz gene is localized on chromosome 19q13.33.

Specifications

• Antigen: FUZ
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FUZ
• Gene Alias: 2600013E07Rik; b2b1273Clo; Fuz; fuzzy homolog; fuzzy homolog (Drosophila); fuzzy planar cell polarity protein; FY; NTD; Protein fuzzy homolog; RGD1310608
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 308577, 80199
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q3B756, Q9BT04
• Gene Symbols: FUZ
• Immunogen: Recombinant protein encompassing a sequence within the center region of human FUZ. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG