Invitrogen™ FUT3/FUT5 Polyclonal Antibody

Sheep Polyclonal Antibody

Brand:  Invitrogen™ PA547569

Product Code. 15538062

Description

Reconstitute at 0.2 mg/mL in sterile PBS.

FUT3 comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This protein is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities.

Specifications

• Antigen: FUT3/FUT5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FUT3
• Gene Alias: 4-fucosyltransferase; alpha (1,3) fucosyltransferase; alpha-(1,3)-fucosyltransferase 5; alpha-(1,3/1,4)-fucosyltransferase; blood group Lewis alpha-4-fucosyltransferase; CD174; FT3B; Fucosyltransferase 3; fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group); fucosyltransferase 3 (Lewis blood group); fucosyltransferase 5; fucosyltransferase 5 (alpha (1,3) fucosyltransferase); fucosyltransferase III; Fucosyltransferase V; FucT-III; FUC-TV; fucT-V; FUT3; FUT5; Galactoside 3(4)-L-fucosyltransferase; galactoside 3-L-fucosyltransferase; LE; Les; Lewis FT; Lewis Y
• Host Species: Sheep
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2525, 2527
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P21217, Q11128
• Gene Symbols: FUT3, FUT5
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human FUT5 Arg35-Thr374.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG