Invitrogen™ FUS Monoclonal Antibody (1FU-1D2)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA3089

Product Code. 15865873

Description

MA3-089 detects AID from human samples MA3-089 has been successfully used in Western blot. The MA3-089 immunogen is the synthetic peptide coupled to ovalalbumin, aa 266 to 283. MA3-089 detects FUS/TLS (~70kDa) in human samples.

This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

Specifications

• Antigen: FUS
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Ascites with 0.05% sodium azide
• Gene Accession No.: P35637
• Gene Symbols: FUS
• Immunogen: Synthetic peptide (GPRDQGSRHDSEQDNSDC) coupled to ovalbumin. From aa 266 to aa 283 of FUS.
• Regulatory Status: RUO
• Gene ID (Entrez): 2521
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Clone: 1FU-1D2
• Conjugate: Unconjugated
• Gene: FUS
• Gene Alias: 16) in malignant liposarcoma); 16) malignant liposarcoma; 75 kDa DNA-pairing protein; ALS6; D430004D17Rik; D930039C12Rik; ETM4; FUS; FUS RNA binding protein; Fus1; fused in sarcoma; fused in sarcoma RNA binding protein; fusion (involved in t(12; fusion gene in myxoid liposarcoma; fusion, derived from t(12; fusion, derived from t(12;16) malignant liposarcoma; fus-like protein; heterogeneous nuclear ribonucleoprotein P2; hnRNP P2; HNRNPP2; oncogene FUS; Oncogene TLS; pigpen protein; POMP75; Protein pigpen; RNA-binding protein FUS; TLS; translocated in liposarcoma; translocated in liposarcoma protein
• Host Species: Mouse
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ