Fumonisin B1, 96%

Product Code. 10741361

Brand: Thermo Scientific Acros 328250010

Descrizione

Fumonisin, CAS # 116355-83-0, also known as Macrofusine, is a cell permeable mycotoxin that is an inhibitor of sphingosine N-acetyl transferase. | CAS: 116355-83-0 | C₃₄H₅₉NO₁₅ | 721.8 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Fumonisin is a fungal metabolite that is a cell permeable mycotoxin that can halt sphingolipid biosynthesis by inhibiting sphingosine N-acetyl transferase

Applications

• It can potently inhibit sphingosine N-acyltransferase (ceramide synthase), causing an accumulation of sphingoid bases

• It is also a protein serine and threonine phosphatase inhibitor

• It can selectively inhibit sphingomyelin biosynthesis in neuronal cells

Specifica

Identificatori chimici

• CAS: 116355-83-0
• Molecular Formula: C₃₄H₅₉NO₁₅
• Molecular Weight (g/mol): 721.8
• MDL Number: MFCD00133349
• InChI Key: UVBUBMSSQKOIBE-UWCNXKJPSA-N
• Synonym: macrofusine, fumonisin b1, 2r,2'r-1,2,3-propanetricarboxylic acid 1,1'-1s,2r-1-2s,4r,9r,11s,12s-12-amino-4,9,11-trihydroxy-2-methyltridecyl-2-1r-1-methylpentyl-1,2-ethanediyl ester, 2s-2-2-5r,6r,7s,9s,11r,16r,18s,19s-19-amino-6-3r-3,4-dicarboxybutanoyl oxy-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl oxy-2-oxoethyl butanedioic acid
• PubChem CID: 16760030
• IUPAC Name: (2S)-2-[2-[(5R,6R,7S,9S,11R,16R,18S,19S)-19-amino-6-[(3R)-3,4-dicarboxybutanoyl]oxy-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid
• SMILES: CCCCC(C)C(C(CC(C)CC(CCCCC(CC(C(C)N)O)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O

• Color: Tan to White
• Elemental Analysis: 55.00 to 58.00%C, 1.60 to 2.20%N
• Assay Percent Range: 95% min. (HPLC)
• Quantity: 1 mg
• Merck Index: 15, 4318
• Solubility Information: Solubility in water: soluble. Other solubilities: soluble in methanol,acetonitrile
• Formula Weight: 721.8
• Percent Purity: 96%
• Physical Form: Powder
• Chemical Name or Material: Fumonisin B1

Sicurezza e movimentazione

Identificativo prodotto

• Fumonisin B1

Avvertenza

• Warning

Categoria di pericolo

• Carcinogenicity Category 2

Indicazioni di pericolo

• H351-Suspected of causing cancer.

Consigli di prudenza

• P280-Wear protective gloves/protective clothing/eye protection/face protection.

SDS

RUO – Research Use Only