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Fulvestrant, MedChemExpress

Product Code. 16455788
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Product Code. 16455788

Brand: Medchem Express HY13636

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Description

MedChemExpress Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy.

Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy.

Specifications

Chemical Name or Material Fulvestrant
CAS 129453-61-8
Color White
Purity Grade Notes Research
Molecular Formula C32H47F5O3S
Quantity 10 mg
Synonym ICI 182780 ZD 9238 ZM 182780
Solubility Information DMSO : 250 mg/mL (412.02 mM; Need ultrasonic)
SMILES C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])[C@H](CCCCCCCCCS(CCCC(F)(F)C(F)(F)F)=O)CC4=C(C=CC(O)=C4)[C@@]3([H])CC2
Molecular Weight (g/mol) 606.77
Formula Weight 606.77
Percent Purity 95.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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