FTO Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16885495	Proteintech 27226-1-AP-20UL	20 μL
16875495	Proteintech 27226-1-AP-150UL	150 μL

Description

Rising obesity rates are rapidly becoming a growing health concern in the developing world. The fat mass and obesity associated gene (FTO) is the first gene discovered to contribute to common forms of human obesity. FTO is a member of the non-heme dioxygenase superfamily, encoding a 2-oxoglutarate-dependent nucleic acid demethylase whose mRNA is widely expressed, especially in neurons of feeding-related nuclei of the brain. FTO mRNA in the arcuate nucleus in mice is up-regulated by feeding and down-regulated during fasting, although the opposite pattern has been observed in rats. At least four isoforms of FTO are known to exist.

Specifications

• Antigen: FTO
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Mouse, Human
• Gene Accession No.: Q8BGW1, Q9C0B1
• Gene ID (Entrez): 26383, 79068
• Immunogen: FTO Fusion Protein Ag26095
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: FTO

• Concentration: 0.5 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: FTO, KIAA1752
• Gene Symbols: FTO
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody