Invitrogen™ FTO Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5120656

Product Code. 17752054

Description

Positive test controls include: Mouse brain, Rat brain. Immunogen sequence: MKPRQRKQYF RNMKRSDDSE REKRRKRRRL LQELGEQRIP YLSPTDPGFQ DLWDSSYAGL ALRQSGTLPE GLHEKVQSAL LTLQRHGCLL RDLVRVRDRD VFTAVSRALV GQPGYTYRYL DTRLFTIPWH CEGEEGQKDE KGKPCCDSDL RDACKALWEL NQFFCSDVKQ QTNARGVKRT RSDTENSEDA PGEGMCEEES VKDRLVEEKT IEEEEEDSGQ GCSHSSPPSS TPPAAQASLV QFNVTLINYM NPAAMTQLKE EPYYGMGKMA VGWHHDENLV PLSPVAVYSY SCPAEPKNEG VTEKDGEGKS KEKEREAKGE GTSTEEVKKE GEASVKEDVE KEKTCWRVG.

FTO is a novel protein and a member of the non-heme dioxygenase (Fe(II)-and 2-oxoglutarate-dependent dioxygenases) superfamily. Amino acid conservation patterns support this hypothesis and indicates that both 2-oxoglutarate and iron should be important for FTO function. Though not much is yet known about FTO, it is thought that the protein may somehow modify the activity of genes involved in metabolism and fat storage, which in turn may influence a person's risk of obesity.

Specifications

• Antigen: FTO
• Classification: Polyclonal
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q2A121, Q8BGW1, Q9C0B1
• Gene Symbols: Fto
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-349 of zebrafish FTO (XP_009301626.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Gene: Fto
• Gene Alias: AlkB homolog 9; ALKBH9; alpha-ketoglutarate-dependent dioxygenase FTO; AW743446; BMIQ14; fat mass and obesity associated; fat mass and obesity-associated protein; fatso; FTO; GDFD; KIAA1752; m6A(m)-demethylase FTO; MGC5149; mKIAA1752; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; Protein fatso; protein fto; RGD1305121; tRNA N1-methyl adenine demethylase FTO; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26383, 291905, 79068
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid