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Invitrogen™ FRS2 Recombinant Rabbit Monoclonal Antibody (K01_2U54)
Description
FRS2 Recombinant Monoclonal Antibody for Western Blot
Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. [UniProt].
Specifications
Specifications
| Antigen | FRS2 |
| Applications | Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | K01_2U54 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 50mM tris glycine with 150mM NaCl, 40% glycerol, 0.05% BSA and 0.01% sodium azide; pH 7.4 |
| Gene | FRS2 |
| Gene Accession No. | Q8WU20 |
| Gene Alias | 4732458E18; C330018A15Rik; FGFR signalling adaptor; FGFR substrate 2; FGFR-signaling adaptor SNT; fibroblast growth factor receptor substrate 2; FRS1A; FRS2; Frs2a; FRS2alpha; FRS2-alpha; SNT; SNT1; SNT-1; SNT2; suc1-associated neurotrophic factor target 1 |
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