Invitrogen™ FRS2 Monoclonal Antibody (462902)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA561381

Product Code. 30534533

Description

Reconstitute at 0.5 mg/mL in sterile PBS.

Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. [UniProt].

Specifications

• Antigen: FRS2
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with trehalose and no preservative
• Gene Accession No.: Q8WU20
• Gene Symbols: FRS2
• Immunogen: E. coli-derived recombinant human FRS2, Asn121-Asn449.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Flow Cytometry
• Clone: 462902
• Conjugate: Unconjugated
• Gene: FRS2
• Gene Alias: 4732458E18; C330018A15Rik; FGFR signalling adaptor; FGFR substrate 2; FGFR-signaling adaptor SNT; fibroblast growth factor receptor substrate 2; FRS1A; FRS2; Frs2a; FRS2alpha; FRS2-alpha; SNT; SNT1; SNT-1; SNT2; suc1-associated neurotrophic factor target 1
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 10818
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized