Invitrogen™ FPR1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5140980

Product Code. 17870296

Description

FPR1 Polyclonal Antibody for Western Blot, IHC (P)

FPR1 is a member of chemoattractant/chemokine GPCRs expressed mainly on leukocytes, neutrophils and monocytes. FPR1 is a seven transmembrane pertussis toxin-sensitive GPCR and binds to formylated peptides generated by bacteria resulting in leukocyte trafficking to the site of inflammation. Ligand binding to FPR results in activation of multiple effectors including phospholipase C leading to calcium mobilization and PKC activation. Other implications of FPR signaling include polarization of actin cytoskeleton, activation of various integrins, increased cell migration, phagocytosis, degranulation and release of reactive oxygen intermediates.

Specifications

• Antigen: FPR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FPR1
• Gene Alias: fMet-Leu-Phe receptor; fMLF-R; FMLP; fMLP receptor; formyl peptide receptor 1; FPR; Fpr receptor; FPR1; FPR-1; lipoxin A4 receptor; LXA4R; N-formyl peptide receptor; N-formylpeptide chemoattractant receptor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14293, 2357
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.2% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P21462, P33766
• Gene Symbols: FPR1
• Immunogen: Synthetic peptide within Mouse FPR1 aa 151-200/364.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG