FOXP3, clone: eBio7979, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-7979-80
Code : Z2
Additional Details : Weight : 0.01000kg
DescriptionDescription: eBioscience offers a panel of monoclonal antibodies to different epitopes of human and mouse Foxp3, providing useful tools for investigating the complete expression pattern of Foxp3 at the protein level, and discerning the precise subsets of Foxp3+ cells. Other antibodies to human Foxp3 include PCH101 (cat. 72-5776) and 236A/E7 (cat. 12-4777). Additional antibodies to mouse Foxp3 include FJK-16s (cat. 72-5775) and NRRF-30 (cat. 12-4771). The eBio7979 antibody reacts with human and mouse foxp3 protein also known as FORKHEAD BOX P3, SCURFIN, and JM2; cross reactivity of this antibody to other proteins has not been determined. Foxp3, a 49-55kDa protein, is a member of the forkhead/winged-helix family of transcriptional regulators, and was identified as the gene defective in 'scurfy' (sf) mice. Constitutive high expression of Foxp3 mRNA has been shown in CD4+CD25+ regulatory T cells (Treg cells), and ectopic expression of foxp3 in CD4+CD25- cells imparts a Treg phenotype in these cells.Please see our FAQ regarding the usage of eBioscience Foxp3 reagents.Applications Reported: This eBio7979 antibody has been reported for use in immunoblotting (WB).Applications Tested: This eBio7979 antibody has been tested by immunoblotting of normal human peripheral blood mononuclear cell lysates at 1-2μg/mL.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.09% sodium azide; pH 7.2|
|AIID, DIETER, Forkhead box P3, foxp3, IPEX, JM2, PIDX, SCURFIN, XPID|
|Store at 2-8°C.|
For Research Use Only.