Invitrogen™ FOXC1 Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA518458

Product Code. 11356433

Description

This antibody is predicted to react with mouse and porcine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

FOXC1 is a protein belonging to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this protein is not known, however, it plays a role in the regulation of FGF19-FGFR4-MAPK pathway to promote both the development and maintenance of anterior segment structures within the eye. Mutations in this gene cause various glaucoma, iridogoniodysgenesis anomaly, Peters anomaly that includes central corneal leukoma, absence of the posterior corneal stroma and Descemetmembrane and Axenfeld-Rieger anomaly characterized by posterior corneal embryotoxon, iris adhesion to the Schwalbe line, hypertelorism, hypoplasia of the malar bones, congenital absence of some teeth and mental retardation.

Specifications

• Antigen: FOXC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FOXC1
• Gene Alias: ARA; ch; congenital hydrocephalus; Fkh1; fkh-1; Fkhl7; forkhead box C1; forkhead box C1 protein; forkhead box protein C1; forkhead, drosophila, homolog-like 7; forkhead/winged helix-like transcription factor 7; forkhead-related activator 3; forkhead-related protein FKHL7; Forkhead-related transcription factor 3; Foxc1; FREAC3; FREAC-3; frkhda; HGNC:3800; IGDA; IHG1; IRID1; Mesoderm/mesenchyme forkhead 1; Mf1; MF-1; Mf4; myeloid factor-delta; RIEG3; Transcription factor FKH-1
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 2296
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q12948
• Gene Symbols: FOXC1
• Immunogen: Synthetic peptide sequence (DAVKDKEEKDRLH) corresponding to the internal amino acids of FOXC1 (aa 178-191).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG