FOXB2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA539169

Product Code. 15536081

Description

The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and maybe associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are membersof the FOX family and each contain one forkhead DNA-binding domain.Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded evelopment of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.

Specifications

• Antigen: FOXB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FOXB2
• Gene Alias: Forkhead box protein B2, FOXB2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14240, 442425
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q5VYV0, Q64733
• Gene Symbols: FOXB2
• Immunogen: A synthetic peptide derived from the internal region of human FOXB2
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG