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Fostamatinib, MedChemExpress

Product Code. 16466086
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Product Code. 16466086 Supplier Medchem Express Supplier No. HY13038A

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Description

MedChemExpress Fostamatinib (R788) is the oral prodrug of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).

Fostamatinib (R788) is the oral prodrug of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).

Specifications

Chemical Name or Material Fostamatinib
CAS 901119-35-5
Color White
Purity Grade Notes Research
Molecular Formula C23H26FN6O9P
Quantity 100 mg
Synonym R788
Solubility Information DMSO : 62.5 mg/mL (107.67 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
SMILES COC1=CC(NC2=NC=C(C(NC3=NC(N4COP(O)(O)=O)=C(C=C3)OC(C)(C)C4=O)=N2)F)=CC(OC)=C1OC
Molecular Weight (g/mol) 580.46
Formula Weight 580.46
Percent Purity 98.61%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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