Forodesine hydrochloride, MedChemExpress

Product Code. 16469547

Brand: Medchem Express HY16209

Description

MedChemExpress Forodesine hydrochloride (BCX-1777 hydrochloride) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine hydrochloride is a potent human lymphocyte proliferation inhibitor. Forodesine hydrochloride could induce apoptosis in leukemic cells by increasing the dGTP levels.

Forodesine hydrochloride (BCX-1777 hydrochloride) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine hydrochloride is a potent human lymphocyte proliferation inhibitor. Forodesine hydrochloride could induce apoptosis in leukemic cells by increasing the dGTP levels.

Specifications

• Chemical Name or Material: Forodesine hydrochloride
• CAS: 284490-13-7
• Color: Brown
• Purity Grade Notes: Research
• Molecular Formula: C₁₁H₁₅ClN₄O₄
• Quantity: 5 mg
• Synonym: BCX-1777 hydrochlorideImmucillin-H hydrochloride
• Solubility Information: H2O : 100 mg/mL (330.35 mM; Need ultrasonic) ∣DMSO : 10 mg/mL (33.03 mM; Need ultrasonic)
• SMILES: O=C1C(NC=C2[C@@H]3N[C@H](CO)[C@@H](O)[C@H]3O)=C2NC=N1.Cl
• Molecular Weight (g/mol): 302.71
• Formula Weight: 302.71
• Percent Purity: 98.35%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-programmed cell death

Research purposes only