Invitrogen™ Folate Receptor alpha Polyclonal Antibody

Sheep Polyclonal Antibody

Brand:  Invitrogen™ PA547884

Product Code. 15588372

Description

In direct ELISAs, approximately 30% cross-reactivity with recombinant human FOLR1 is observed. Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: Folate Receptor alpha
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FOLR1
• Gene Alias: 66/67kDa; AA407891; adult folate-binding protein; eIF3 p66; EIF3D; eIF3d {ECO:0000255; eIF3p66; eIF3-p66; EIF3S7; eIF-3-zeta; eIF3-zeta; eIF-3-zeta {ECO:0000255; Eukaryotic translation initiation factor 3 subunit 7; eukaryotic translation initiation factor 3 subunit 7 {ECO:0000255; eukaryotic translation initiation factor 3 subunit D; eukaryotic translation initiation factor 3 subunit D {ECO:0000255; eukaryotic translation initiation factor 3, subunit 7 (zeta); eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa; eukaryotic translation initiation factor 3, subunit D; FBP; Fbp1; folate binding protein; folate binding protein 1; folate receptor 1; folate receptor 1 (adult); folate receptor alpha; Folate receptor, adult; folate-binding protein 1; Folbp1; Folbp-1; FOLR; FOLR1; FR-alpha; HAMAP-Rule:MF_03003}; KB cells FBP; MOv18; Ovarian tumor-associated antigen MOv18; translation initiation factor eIF3 p66; translation initiation factor eIF3 p66 subunit
• Host Species: Sheep
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14275
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Frozen), Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P35846
• Gene Symbols: FOLR1
• Immunogen: CHO-derived recombinant mouse FOLR1 Arg23-Ser232.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG