Invitrogen™ FNTB Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA597757

Product Code. 16580582

Description

FNTB Polyclonal Antibody for ELISA, ICC/IF, IHC (P), IP, Western Blot

Eukaryotic cells contain 3 different types of prenyltransferases that attach either a farnesyl group (15 carbons) or a geranylgeranyl group (20 carbons) in thioether linkage to C-terminal cysteine residues in a variety of proteins. These posttranslational modifications provide a mechanism for membrane localization of proteins that lack a transmembrane domain. CAAX farnesyltransferase (FTase) attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This enzyme has the ability to farnesylate peptides as short as 4 residues in length that conform to the CAAX consensus sequence. The gene for the beta subunit of CAAX farnesyltransferase (FNTB) has been pinpointed to 14q23-q24 by Southern blot hybridization and PCR analyses of panels of human/Chinese hamster somatic cell hybrid lines and by fluorescence chromosomal in situ hybridization.

Specifications

• Antigen: FNTB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FNTB
• Gene Alias: 2010013E13Rik; AA409500; CAAX farnesyltransferase subunit beta; EC 2.5.1.58; farnesyl-protein transferase beta-subunit; farnesyltransferase beta subunit; farnesyltransferase, CAAX box, beta; FNTB; FPTB; ft beta; FTase beta; FTase-beta; LOW QUALITY PROTEIN: protein farnesyltransferase subunit beta; protein farnesyltransferase subunit beta; Ras proteins prenyltransferase subunit beta
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 2342
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry, Western Blot
• Concentration: 3 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: P49356
• Gene Symbols: FNTB
• Immunogen: Recombinant Human Protein farnesyltransferase subunit beta protein (1-300AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG