Invitrogen™ FNDC4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA562486

Product Code. 15730282

Description

Immunogen sequence: IKDNDSNNNP KEKGKGPEQS PQGRPVGTRQ KKSPSINTID V Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 100%.

Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis.

Specifications

• Antigen: FNDC4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FNDC4
• Gene Alias: 2810430J06Rik; 6330410H20Rik; AB030187; AI838506; AW487863; fibronectin type III domain containing 4; fibronectin type III domain-containing protein 4; fibronectin type III repeat containing protein 1; fibronectin type III repeat-containing protein 1; Fndc4; Fnmp1; FRCP1; UNQ6389/PRO21134
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64838
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9H6D8
• Gene Symbols: FNDC4
• Immunogen: Recombinant protein corresponding to Human FNDC4. Recombinant protein control fragment (Product #RP-101209).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG