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Description
The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.
Specifications
Specifications
| Antigen | FMO2 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 0.14 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | FMO2 |
| Gene Accession No. | Q6IRI9, Q8K2I3, Q99518 |
| Gene Alias | Dimethylaniline oxidase 2, FMO 1B1, FMO 2, FMO1B1, FMO2 |
| Gene Symbols | Fmo2 |
| Show More |
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