Invitrogen™ FMO1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA569138

Product Code. 15807553

Description

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%.

Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics.

Specifications

• Antigen: FMO1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FMO1
• Gene Alias: dimethylaniline monooxygenase [N-oxide-forming] 1; Dimethylaniline oxidase 1; fetal hepatic flavin-containing monooxygenase 1; flavin containing dimethylaniline monoxygenase 1; flavin containing monooxygenase 1; Flavin-containing monooxygenase 1; Flavin-containing monooxygenase 1 (fetal liver); FMO 1; FMO 1A1; FMO form 1; Fmo1; Fmo-1; hepatic flavin-containing monooxygenase (EC 1.14.13.8); hepatic flavin-containing monooxygenase (FMO); hepatic flavin-containing monooxygenase 1; monooxygenase (FMO) (EC 1.14.13.8); RFMO1A
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25256
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P36365
• Gene Symbols: FMO1
• Immunogen: synthetic peptide directed towards the middle region of human FMO1 (aa 40-89).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG