Invitrogen™ FMNL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA534477

Product Code. 15385401

Description

A suggested positive control is EL4 cell lysate. PA5-34477 can be used with blocking peptide PEP-1519.

The Formin-like protein 1 (FRL1) gene encodes a formin-related protein which has been implicated in morphogenesis, cyokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and have one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain and one GBD/FH3 (Rho GTPase-binding / formin homology 3) domain. FRL1 is located in the cytoplasm and is highly expressed in the spleen, lymph node and bone marrow cells. FRL1 possibly has a role in the control of cell motility, survival of macrophages and cytoskeletal organization.

Specifications

• Antigen: FMNL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FMNL1
• Gene Alias: 8030453N10Rik; AI553564; C17orf1; C17orf1B; CLL-associated antigen KW-13; FHOD4; Fmnl; Fmnl1; Fnrl; formin like 1; formin-like 1; formin-like protein 1; formin-related gene in leukocytes; formin-related protein; Frl; FRL1; Frls; KW-13; Leukocyte formin; lymphocyte specific formin related protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 287746, 57778, 752
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: O95466, Q9JL26
• Gene Symbols: FMNL1
• Immunogen: A 16 amino acid peptide near the carboxy terminus of human FRL1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG