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  5. STEMCELL Technologies (±)-Flurbiprofen

STEMCELL Technologies (±)-Flurbiprofen

Product Code. 17160292
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5 g
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Product Code. 17160292 Supplier STEMCELL Technologies Supplier No. 73924

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Description

PI3K/AKT pathway inhibitor; Inhibits COX-1 and COX-2

  • (±)-Flurbiprofen is a cell-permeable and non-steroidal anti-inflammatory agent
  • It is a potent non-selective inhibitor of cyclooxygenase (COX) with EC50 = 0.1 and 0.4 μM for the inhibition of recombinant human COX-1 and COX-2, respectively (Gierse et al.)
  • Maintains self-renewal and pluripotency in hESC cells grown in conditions that induce differentiation (Bhanu et al.; Desbordes et al.)
  • Inhibits tumor growth in models of prostate cancer, familial adenomatous polyposis, and brain cancer (King, Jr & Khalili; Grubbs et al.; Wechter et al.; Zemskova et al.)

Specifications

CAS 5104-49-4
Synonym Ansaid
Quantity 5 g
Molecular Formula C15H13FO2
Purity ≥99%
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