Fluorescein-CREBtide Substrate

Fluorescein-CREBtide Substrate

Brand:  Invitrogen PV3508

Product Code. 10423082

Description

A fluorescein-labeled peptide substrate that is based upon the CREB ( cAMP responsive element binding) protein. The peptide substrate is phosphorylated by a wide range of Ser/Thr kinases.

For use in combination with the LanthaScreen™ Tb-CREB [pSer133] antibody (PV3542) to evaluate inhibitors in medium to high throughput screening applications.

Specifications

• Amino Acid Sequence: Fluorescein- KRREILSRRPSYR
• Content And Storage: 1 mg/mL Fluorescein-CREBtide substrate in water. Store at -20°C and protect from light.
• Quantity: 1 mg
• Substrate Properties: Peptide-Based Substrate
• Target Enzyme: Serine/Threonine Kinases
• Molecular Weight (g/mol): 2076 Da
• Target Entry: AMPK (A2/B1/G1), STK22D, CAMK2B, CHEK1, MAPKAPK2, PASK, PIM2, PRKCN, PRKD2, PRKG2, RPS6KA5, AMPK (A1/B1/G1), AURKA, CAMK1D, CAMK4, CHEK2, MAPKAPK3, PIM1, PKN1, PRKD1, PRKG1, RPS6KA4, CAMK1

• Assay Entry: Biochemical terbium phospho-specific activity
• Detection Method: Fluorescence
• Substrate: Fluorescein-CREBtide
• Substrate Type: Kinase Substrate
• Label or Dye: FITC (Fluorescein)
• Shipping Condition: Dry Ice
• Validated Kinases: AMPK, AURKA, CAMK1, CAMKID, CAMK2A, CAMK2B, CAMK4, CHEK1, CHEK2, MAPKAPK2, MAPKAPK3, PASK, PIM1, PIM2, PKN1, PRKACA, PRKD1, PRKD2, PRKG1, PRKG2, RPS6KA4, RPS6KA5, STK22D

For Research Use Only. Not for use in diagnostic procedures.