Invitrogen™ FLASH Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA519954

Product Code. 12888162

Description

In Western blot applications, this antibody detects a band at ~220kDa. A suggested positive control is Hela cell lysate. PA5-19954 can be used with blocking peptide PEP-0079.

This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.

Specifications

• Antigen: FLASH
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CASP8AP2
• Gene Alias: AA387232; CASP8 associated protein 2; CASP8AP2; CASP8-associated protein 2; caspase 8 associated protein 2; CED-4; D4Ertd659e; FLASH; FLASH homolog RIP25; FLICE associated huge; FLICE-associated huge protein; FLJ11208; human FLASH; KIAA1315; mKIAA1315; RIP25; RP11-63K6.3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9994
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q9UKL3
• Gene Symbols: CASP8AP2
• Immunogen: A synthetic peptide corresponding to amino acids near the carboxy terminus of human FLASH.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG