FIV gp95 Antibody (SU1-30), DyLight 550, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NB100-64378R

Product Code. 18021516

Description

FIV gp95 Monoclonal specifically detects FIV gp95 in Virus samples. It is validated for Western Blot, Flow Cytometry.

Specifications

• Antigen: FIV gp95
• Classification: Monoclonal
• Conjugate: DyLight 550
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Immunogen: Made to FIV gp95
• Quantity: 0.125 mL
• Test Specificity: NB100-64378 specifically recognizes the relatively conserved E60 peptide (amino acid sequence SSWKQRNRWEWRPDF) located within the V3 region of FIV (Feline Immunodeficiency Virus) envelope glycoprotein SU,gp95. The primary receptor for FIV infection of cats has been identified as the T-cell activation antigen CD134 which, along with CXC chemokine receptor 4 (CXCR4), facilitates the infection of CD4+ primary target cells, resulting in a depletion in the CD4+ population. Studies have shown that the V3 loop of SU,gp95 is a major immunogenic domain, suggested to contain the main determinants for the binding of FIV SU,gp95 to CXCR4.(3) Clone SU1-30 has been shown to inhibit the sCD134-activated entry of both clade B and clade C FIV strains.(1) NB100-64378 does not recognize Feline Leukaemia Virus, Feline Herpes Virus type 1, Feline Coronavirus or Feline Calicivirus. Removal of Sodium Azide is recommended prior to use in functional studies.
• Content And Storage: Store at 4°C in the dark.

• Applications: Western Blot, Flow Cytometry
• Clone: SU1-30
• Dilution: Western Blot, Flow Cytometry
• Host Species: Mouse
• Purification Method: Protein A purified
• Primary or Secondary: Primary
• Target Species: Virus
• Isotype: IgG1