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  6. Invitrogen™ FIS1 Recombinant Rabbit Monoclonal Antibody (K01_2J65)

Invitrogen™ FIS1 Recombinant Rabbit Monoclonal Antibody (K01_2J65)

Product Code. 30828079
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50 μL
100 μL
Unit Size:
100µL
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30828079 50 μL -
30825578 100 μL 100µL
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Product Code. 30828079 Supplier Invitrogen™ Supplier No. MA565358
 Restricted Item
Estimated Shipment: 24-09-2026
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: LVSVEDLLKF EKKF.

Fis1, a 17KDa integral membrane protein, is a novel member of mitochondrial fission machinery. It consists of a central leucine-zipper domain, a coiled-coil region, a tetratricopeptide repeat domain and a C-terminal transmembrane domain. It is a human orthologue of Fis1p (S.cerevisiae) and is localized in the outer mitochondrial membrane. Fis1 acts as a pro-apoptotic factor and plays a vital role in the regulation of mitochondrial fission. It interacts with DLP1 and Mdv1p and facilitates Dnm1p recruitment to the functional fission complex, thereby inducing apoptosis. Role of Fis1 has also been implicated in growth and division of peroxisomes. Loss of Fis1 inhibits apoptosis and results in elongation of mammalian mitochondria.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FIS1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone K01_2J65
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 40% glycerol, 0.05% BSA, 150mM NaCl and 0.01% sodium azide; pH 7.4
Gene FIS1
Gene Accession No. Q9Y3D6
Gene Alias 2010003O14Rik; CGI-135; Fis1; fis1 {ECO:0000250; FIS1 homolog; fission 1 (mitochondrial outer membrane) homolog; fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae); fission 1 (mitochondrial outer membrane) homolog (yeast); fission, mitochondrial 1; H_NH0132A01.6; hFis1; Mitochondrial fission 1 protein; mitochondrial fission molecule; rFis1; tetratricopeptide repeat domain 11; tetratricopeptide repeat protein 11; TPR repeat protein 11; TTC11; UniProtKB:Q9Y3D6}
Gene Symbols FIS1
Host Species Rabbit
Immunogen A synthetic peptide of human TTC11 (aa 8-21).
Purification Method Protein A/G
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51024
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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