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Filgotinib, MedChemExpress

Product Code. 16483517
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16483517 50 mg 50mg
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Product Code. 16483517 Supplier Medchem Express Supplier No. HY18300

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Description

MedChemExpress Filgotinib (GLPG0634) is a selective and orally active JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively.

Filgotinib (GLPG0634) is a selective and orally active JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively.

Specifications

Chemical Name or Material Filgotinib
CAS 1206161-97-8
Color White
Purity Grade Notes Research
Molecular Formula C21H23N5O3S
Quantity 50 mg
Synonym GLPG0634
Solubility Information DMSO : 25 mg/mL (58.75 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES O=C(C1CC1)NC2=NN3C(C4=CC=C(CN5CCS(CC5)(=O)=O)C=C4)=CC=CC3=N2
Molecular Weight (g/mol) 425.5
Formula Weight 425.5
Percent Purity 98.08%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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