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Invitrogen™ Filaggrin 2 Polyclonal Antibody
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Product Code. 15703871 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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15703871 100 μL 100µL
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Product Code. 15703871 Supplier Invitrogen™ Supplier No. PA555951

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Rabbit Polyclonal Antibody

Immunogen sequence: CGYSNSSGCG RPQNASSSCQ SHRFGGQGNQ FSYIQSGCQS GIKGGQGHGC VSGGQPSGCG QPESNPCSQS YSQRGYGARE NGQPQNCGGQ WRTGSSQSSC CG Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 35%.

The FLG2 protein is upregulated by calcium, proteolyzed by calpain 1, and is involved in epithelial homeostasis. FLG2 is also required for proper cornification in skin, with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact, in addition to providing a physical barrier, C-terminal fragments of this protein display antimicrobial activity against P. aeruginosa.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Filaggrin 2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene FLG2
Gene Accession No. Q5D862
Gene Alias filaggrin family member 2; filaggrin-2; FLG2; FLG-2; Ifapsoriasin; IFPS; intermediate filament-associated and psoriasis susceptibility protein; intermediate filament-associated and psoriasis-susceptibility protein
Gene Symbols FLG2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human Filaggrin 2. Recombinant protein control fragment (Product #RP-94294).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 388698
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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