Invitrogen™ Ficolin 3 Monoclonal Antibody (296134)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA524004

Product Code. 15573692

Description

In direct ELISAs and Western blots, no cross-reactivity with recombinant human Ficolin-2 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

H-Ficolin (Hakata antigen, Ficolin-3) is an innate immunity pattern recognition molecule found in human serum. H-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP) formed by carbohydrates (GlcNAc, GalNAc and fucose) activating complement through the lectin pathway by means of the associated MASPs ((MBL)-associated serine proteases). H-Ficolin consists of 35 kDa protein chains associated in triplet subunits which are again associated in high molecular weight oligomers by means of disulfide bonds at the N-terminal region.

Specifications

• Antigen: Ficolin 3
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: O75636
• Gene Symbols: FCN3
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Ficolin-3 Isoform 2 Lys22-Arg288.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot
• Clone: 296134
• Conjugate: Unconjugated
• Gene: FCN3
• Gene Alias: Collagen/fibrinogen domain-containing lectin 3 p35; Collagen/fibrinogen domain-containing protein 3; FCN3; FCNH; ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); ficolin 3; ficolin-3; HAKA1; Hakata antigen; LOW QUALITY PROTEIN: ficolin-3; MGC22543
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 8547
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized