Invitrogen™ Fibrinogen gamma Monoclonal Antibody (K24024_2E1), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA556227

Product Code. 30202320

Description

Sequence of this protein is as follows: KVDKDLQSLE DILHQVENKT SEVKQLIKAI QLTYNPDESS KPNMIDAATL KSRKMLEEIM KYEASILTHD SSIRYLQEIY NSNNQKIVNL KEKVAQLEAQ

The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.

Specifications

• Antigen: Fibrinogen gamma
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
• Gene Accession No.: P02679
• Gene Symbols: Fgg
• Immunogen: Recombinant human FGG (immunogen range is 61-160).
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: K24024_2E1
• Conjugate: Unconjugated
• Gene: Fgg
• Gene Alias: 3010002H13Rik; AI256424; FGG; fibg; fibrinogen; fibrinogen gamma chain; Fibrinogen gamma-B chain; fibrinogen gamma-chain; fibrinogen, gamma polypeptide; gamma'; gamma-fibrinogen; PRO2061; testicular tissue protein Li 70; Unknown (protein for MGC:127951)
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2266
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid