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Fibrin beta-chain Antibody (8E5), DyLight 550, Novus Biologicals™

Product Code. 18364121 Shop All Bio Techne Products
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Product Code. 18364121 Supplier Novus Biologicals Supplier No. NBP281110R

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Description

Mouse Monoclonal Antibody

Fibrin beta-chain Monoclonal specifically detects Fibrin beta-chain in Human samples. It is validated for ELISA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Fibrin beta-chain
Applications ELISA
Classification Monoclonal
Clone 800000
Conjugate DyLight 550
Dilution ELISA
Formulation 50mM Sodium Borate
Gene Alias Beta-Fibrinogen, epididymis secretory sperm binding protein Li 78p, fibrinogen beta chain, fibrinogen, B beta polypeptide, HEL-S-78p
Gene Symbols FGB
Host Species Mouse
Immunogen 8E5 was prepared fusing Sp2/o myeloma cells with spleen cells derived from female BALB/c mice immunized with a synthetic beta-fibrin peptide seqeunce GHRPLDKC conjugated to MB-KLH (maleimidobenzoylated keyhole limpet hemocyanin).
Purification Method Protein A purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cell Cycle and Replication
Primary or Secondary Primary
Gene ID (Entrez) 2244
Test Specificity 8E5 binds to the amino-terminal region of the beta-chain of human fibrin at an epitope consiting of GHRPLDKC. Binding is possible in both the monomeric form and the polymeric form of the protein. This peptide sequence is found only in fibrin, and not in its precursor fibrinogen and so there is no cross-reactivity with fibrinogen. Fibrin is a non-globular protein which plays a role in the clotting of blood and circulates as the precursor fibrinogen. Polymerization occurs through the action of the protease thrombin, which results in the active fibrin. Fibrin polymerizes as an insoluble matrix and forms a clot along with platelets over a wound site.
Target Species Human
Content And Storage Store at 4°C in the dark.
Form Purified
Isotype IgG1 κ
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