Invitrogen™ Fibrillin 1 Monoclonal Antibody (CL0226)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA534973

Product Code. 17115643

Description

Immunogen sequence: DVRPGYCYTA LTNGRCSNQL PQSITKMQCC CDAGRCWSPG VTVAPEMCPI RATEDFNKLC SVPMVIPGRP EYPPPPLGPI PPVLPVPPGF PPGPQIPVPR PPVEYLYPSR EPPRVLPVNV TDYCQLVRYL CQNGRCIPTP GSCRCEC Highest antigen sequence indentity to the following orthologs: Rat - 89%, Mouse - 89%.

Fibrillin 1 is an extracellular acidic protein with a high cysteine content and an extended thread-like shape with mosaic composition of different types of extracellular modules. Most of the fibrillin molecule is contributed by 47 epidermal growth factor-like (EGF-like) repeats; 43 of them have a consensus sequence for calcium binding (cb). Other modules including 8-cysteine motifs (seven), hybrid motifs (two), and unique domains (three) are interspersed throughout the molecule[3-7]. Fibrillin 1 contains a proline-rich region close to the N-terminus that is replaced by a glycine-rich region in Fibrillin 2. The fibrillins are found throughout the connective tissue as integral components of extended fibrils.

Specifications

• Antigen: Fibrillin 1
• Classification: Monoclonal
• Concentration: 0.7 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P35555
• Gene Symbols: FBN1
• Immunogen: Recombinant protein fragment of Human FBN1 (Product #RP-90822)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin)
• Clone: CL0226
• Conjugate: Unconjugated
• Gene: FBN1
• Gene Alias: ACMICD; AI536462; Asprosin; B430209H23; ECTOL1; FBN; Fbn1; Fbn-1; Fib-1; fibrillin 1; fibrillin 15; fibrillin-1; GPHYSD2; MASS; MFLS; MFS1; MP340; OCTD; putative; SGS; SSKS; tight skin; Tsk; WMS; WMS2
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2200
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid