Invitrogen™ FGF18 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5106562

Product Code. 16692995

Description

Antibody detects endogenous levels of total FGF18.

FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.

Specifications

• Antigen: FGF18
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Fgf18
• Gene Alias: D130055P09Rik; FGF; FGF18; FGF-18; Fibroblast growth factor; Fibroblast growth factor 18; UNQ420/PRO856; zFGF5
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14172, 8817
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O76093, O89101
• Gene Symbols: Fgf18
• Immunogen: A synthesized peptide derived from human FGF18(Accession O76093), corresponding to amino acid residues E135-L185.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG