FEZ1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA520396

Product Code. 12828582

Description

Despite its predicted molecular weight, FEZ1 often migrates at a higher molecular weight in SDS-PAGE. A suggested positive control is SK-N-SH cell lysate. PA5-20396 can be used with blocking peptide PEP-0513.

This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described.

Specifications

• Antigen: FEZ1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Fez1
• Gene Alias: F37; fasciculation and elongation protein zeta 1; fasciculation and elongation protein zeta 1 (zygin I); fasciculation and elongation protein zeta-1; Fez1; protein kinase C-binding protein Zeta1; UNC76; UNC-76; zygin 1; zygin I; Zygin-1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 235180, 81730, 9638
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P97577, Q8K0X8, Q99689
• Gene Symbols: Fez1
• Immunogen: A 19 amino acid peptide from near the carboxy terminus of human FEZ1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG