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Invitrogen™ Ferritin Monoclonal Antibody (523)

Product Code. 12807982
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1 mg
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Product Code. 12807982 Supplier Invitrogen™ Supplier No. MIF2503

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Description

Mouse Monoclonal Antibody

MIF2503 detects Ferritin in ELISA, IP, IF, and RIA applications and shows reactivity to human samples. The MIF2503 Immunogen is human liver ferritin. MIF2503 detectsferritin which has a predicted molecular weight of approximately 19kDa. MIF2503 was formerly sold as a Seradyn product.

Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. Ferritin is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in the light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. The ferritin gene has multiple pseudogenes, and ferritin is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis. Ferritin is a holoenzyme shell with a molecular weight of about 450 kDa, and consists of 24 subunits of two types, H(heavy) and L(light), and capable of storing up to 4,500 atoms of ferric iron.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Ferritin
Applications ELISA, Immunoprecipitation, Radioimmune Assays (RIA), Immunocytochemistry
Classification Monoclonal
Clone 523
Concentration 5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene FTL
Gene Accession No. P02792, P02794
Gene Alias apoferritin; cell proliferation-inducing gene 15 protein; Ferritin H subunit; ferritin heavy chain; ferritin heavy chain 1; Ferritin heavy chain, N-terminally processed; Ferritin L subunit; ferritin L-chain; ferritin light chain; ferritin light polypeptide-like 3; Ferritin subunit H; ferritin, heavy polypeptide 1; ferritin, light polypeptide; FHC; frih; fril; FTH; Fth1; FTHL6; FTL; HFE5; H-ferritin; HFt; L apoferritin; LFTD; MFH; MGC71996; NBIA3; OK/SW-cl.84; PIG15; placenta immunoregulatory factor; PLIF; proliferation-inducing protein 15
Gene Symbols FTH1, FTL
Host Species Mouse
Immunogen Human liver ferritin.
Purification Method Protein A
Quantity 1 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2495, 2512
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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