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Eurofins DiscoverX Fer Protein, Active
Description
FER (TYK3) is a nuclear and cytoplasmic nonreceptor tyrosine kinase and able to affect transcription in the nucleus. FER is expressed predominantly in mature hematopoietic cells of the granulocytic and monocytic lineage, implicated in the regulation of myeloid differentiation. Inhibition of FER may be of benefit for the treatment of myeloid and prostate cancer as well as angiogenesis.
GenBank NM_005246
Specifications
Specifications
| Formulation | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. 20 mM sodium β-glycerophosphate, 10 mM sodium fluoride, 0.25 mM sodium vanadate. Frozen solution. |
| Molecular Weight (g/mol) | 35.6 kDa |
| Quantity | 10 μg |
| Species | Human |
| Recombinant | Recombinant |
| Protein Tag | N-terminal 6His |
| Expression System | Recombinant enzyme expressed in Sf21 insect cells |
| Protein Form | Truncated |
| Purity or Quality Grade | ≥60% |
| Protein | Fer, active |
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