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Tocris Bioscience™ Fenobam
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Product Code. 30001442
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 30001442

Brand: Tocris Bioscience™ 2386/10

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This item is not returnable. View return policy

Description

Potent and selective mGlu5 negative allosteric modulator (NAM)

Potent and selective non-competitive mGlu5 negative allosteric modulator (NAM) that also displays inverse agonist properties; blocks mGlu5 constitutive activity in vitro (IC50 = 87 nM). Acts at an allosteric modulatory site shared with MPEP and binds the mGlu5 receptor with Kd values of 54 and 31 nM for rat and human receptors respectively. Displays anxiolytic activity following oral administration in vivo; also exhibits analgesic properties.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 57653-26-6
Molecular Formula C11H11ClN4O2

Specifications

Quantity 10 mg
Formula Weight 266.69
Purity >99%
Molecular Weight (g/mol) 266.69
Chemical Name or Material Fenobam
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